Interestingly, Wang Rong et al. [39] and Jiang Tao et al. [40] respectively performed meta-analysis to estimate the prognostic value of Ecto-5′-nucleotidase expression in human cancers, and consistently found high Ecto-5′-nucleotidase expression was an efficient biomarker predicting unfavorable prognosis in human cancers. The gene discussed is NT5E; the disease is cancer.