FOXM1 overexpression was significantly associated with a high TNM stage, lymph node metastasis, patients with a history of smoking [29], poor tissue differentiation, poor disease-free survival [28, 43], low response rate, poor progression-free survival, overall survival [23], and poor relapse-free survival [37]. Here, FOXM1 is linked to metastatic malignant neoplasm in the lymph nodes.