Here we observed that the percentage of recurrent PC was the highest in the low CD8+ T cells infiltration/high PD-L1 expression group (85%, n = 13), followed by the high CD8+ T cells infiltration/high PD-L1 expression group (70%, n = 30), the high CD8+ T cells infiltration/low PD-L1 expression group (61%, n = 13), and the low CD8+ T cells infiltration/low PD-L1 expression group (60%, n = 30). This evidence concerns the gene CD8A and pachyonychia congenita.