PITX3 and lens disorder: Due to the similarity of the lens pathology of the Aey69 mutants with the Pitx3 mutant mouse aphakia (ak) (Semina et al., 2000; Ahmad et al., 2013), we also tested for the immunohistochemical distribution of GJA8 in the aphakia mouse (the absence of Cryaa transcripts in the developing lens was reported earlier by Grimm et al., 1998).