This analysis showed no significant differences in CD4+CD25hiCD127low/− T cell frequencies between treated RA and untreated RA (p>0.05) (Fig. 2a), including using DMARDs or no DMARDs (p>0.05) (Fig. 2b), using steroids or no steroids (p>0.05) (Fig. 2c), and using TNFi or no TNFi (p>0.05) (Fig. 2d). Here, CD4 is linked to rheumatoid arthritis.