MEN1 and digestive system neuroendocrine tumor, grade 1/2: Awaiting more information about the age of disease development including gastrointestinal neuroendocrine tumors, it appears prudent to screen for manifestations of MEN4 with biochemical tests and imaging (e.g., MRI, CT, or endoscopic ultrasound), as recommended in guidelines for evaluation of patients with MEN1 (1).