In fact, JNK and NF-κB pathways play both tumor promoting and tumor suppressive roles (Das et al., 2011; Hui et al., 2008; Inokuchi et al., 2010; Luedde et al., 2007; Maeda et al., 2005; Sakurai et al., 2006). The gene discussed is MAPK8; the disease is neoplasm.