TGFB1 and ductal breast carcinoma in situ: Integrating the common findings in target prediction database and PanCancer pathway analyses, we selected TGFβRII as a main potential direct target of both miR-106b-5p and miR-17-5p, and hypothesized that aberrant expression of these miRNAs might down-regulate the TGF-β pathway to play an important role in the recurrence and progression of DCIS.