The genes most frequently showing CNGs in HAS tumour tissues were TOP1 (50.0%), STK4 (45.5%), CDKN1B (40.9%), H3F3A (36.4%), MYC (22.7%), CCNE1 (22.7%), NFKBIA (22.7%), VEGFA (18.2%), CCND3 (13.6%), and E2F1 (13.6%). The gene discussed is CCNE1; the disease is neoplasm.