PLAU and nasopharyngeal carcinoma: In the comparison of GD patients vs. NPC patients the most remarkable relative fold change (rFC) in expression after qRT-PCR analysis was observed for MX1 and PLAU genes with up-regulated expression (rFC 6.7 and 2.6, respectively) and for ATOH8, MXRA5 and MN1 with down-regulated expression (rFC 0.02, 0.14 and 0.13, respectively), see Fig. 3.