LINC01140 and idiopathic pulmonary fibrosis: In contrast, LINC01140 knockdown in IPF fibroblasts resulted in a ~4–7 fold increase in IL-6 mRNA expression (Fig. 8B) and ~2–3 fold increase in IL-6 release (Fig. 8C) although the variability between patients meant that this was only significant with LNA1.