We herein showed that CEP120 directly interacts with C2CD3 (Fig. 5c) and Talpid3 (Fig. 5f), making it particularly notable that mutations in all three encoding genes reportedly give rise to a similar spectrum of ciliopathies, including the overlapping clinical features of JS and JATD26,27,50–53. The gene discussed is KIAA0586; the disease is ciliopathy.