In addition, BRD4 methylation levels at the cg19287817 locus were found to be lower in cancer tissues than in normal tissues in BLCA, BRCA, cholangiocarcinoma, KIRC, KIRP, liver hepatocellular carcinoma, LUAD, LUSC, pheochromocytoma and paraganglioma, and thyroid carcinoma (Fig. S2c). The gene discussed is BRD4; the disease is hereditary pheochromocytoma-paraganglioma.