The viability of cancer cells treated with the combination of JQ1 and knockdown of ATG5 (Fig. 7j) or ATG7 (Fig. 7k) or the combination of JQ1 and 3-MA (Fig. 7l) or DFO (Fig. 7m) was increased compared to that of cells treated with JQ1 alone; however, treatment with knockdown of ATG5 or ATG7 or treatment with either 3-MA or DFO alone did not enhance cell viability. The gene discussed is ATG5; the disease is cancer.