To further investigate whether LINC01354 regulated proliferation and metastasis in CRC cells through Wnt/β-Catenin signaling, pcDNA3.1/LINC01354-transfected HCT116 cells were treated with DKK1, the secreted antagonist of Wnt/β-Catenin signaling, for rescue assays. This evidence concerns the gene DKK1 and colorectal carcinoma.