ETS1 and osteosarcoma: For example, lncRNA PTTG3P contributes to the proliferation and metastasis of HCC cells through modulating PTTG1 via activating PI3K/AKT signaling in hepatocellular carcinoma [11]; Li D. et al. reported that Ets-1 promoter-associated lncRNA could drive the progression of gastric cancer through regulating NONO/ERG/Ets-1 axis [12]; Wang Y. et al. demonstrated that lncRNA DANCR, severing as a competitive endogenous RNA, contributes to ROCK1-mediated proliferation and metastasis through decoying of miR-335-5p and miR-1972 in osteosarcoma [13].