For example, Fang et al. reported that increased miR-582-3p expression induces lung cancer recurrence through activating Wnt/β-catenin signaling by simultaneously inhibiting multiple inhibitors of Wnt/β-catenin signaling, such as AXIN2, DKK3 and SFRP1 [27]. This evidence concerns the gene SFRP1 and lung carcinoma.