TG metabolites, i.e., chylomicrons, very low-density lipoprotein, and remnant-like particle cholesterol, which are TG-rich lipoproteins, and, apolipoprotein (apo) C-II, and apo C-III which are involved in the metabolic process, etc., have been demonstrated to be involved in the progression of atherosclerosis [41]. The gene discussed is APOC3; the disease is atherosclerosis.