MCHR2 and chondrosarcoma: This clone includes previously known mutations, such as that previously found by Sanger sequencing in IDH2 (R172G) [2,4] or mutations in COL2A1 (G939Wfs*5 and P668Lfs*120) [5,6], as well as other unreported non-synonymous mutations presenting high scores in impact prediction algorithms, such as VNN2, CACNA1D, MCHR2, UNC5D, or MAML2, which possibly contribute to chondrosarcoma progression must be studied in detail.