The GBM-associated microglia and macrophages (GAMMs) system is composed of cluster of differentiation (CD)11b+/CD45dim activated resident microglia (15%), mainly localized in peritumoral areas, and by an infiltrate of CD11b+/CD45high peripheral monocyte-derived macrophages (85%), located in perivascular regions [50]. Here, ITGAM is linked to glioblastoma.