Together with MAPK pathways, the map includes detailed reconstructions in the context of melanoma, e.g., for, growth factor receptors signaling, TNFα signaling, AKT pathway, p53 and BCL-2-linked apoptosis, WNT and NOTCH pathways, cell cycle regulation, hypoxia-induced signaling, and E-cadherin and integrin-mediated signaling. Here, AKT1 is linked to melanoma.