An extract of Aralia elata (a plant traditionally used to treat diabetes in Eastern countries) containing phenolic compounds (3, 4-dihydroxybenzoic acid, chlorogenic acid, and caffeic acid) has been recently shown to reduce glial activation, to suppress NF-κB expression, and to decrease its O-GlcNAcylation in the retinas of STZ diabetic mice [94]. Here, NFKB1 is linked to diabetes mellitus.