Nrf2 has been reported to be regulated by several miRNAs including miR-28 in breast cancer cells MCF-7 and embryonic kidney cells 293T (HEK293T) [50] and miR-153 in breast cancer cell lines [51], neuroblastoma cells [52,53], glioma stem cells [54] and primary hippocampal neurons [55]. This evidence concerns the gene NFE2L2 and central nervous system cancer.