CD40LG and peripheral neuropathy: In general, the advanced tumors with higher stages intend to have a poorer prognosis and they are more likely to affect the nervous system.[8] Based on other reports of lymphoma with immune-mediated neuropathy caused by anti-disialosyl ganglioside IgM antibodies, we propose that the early diagnosis and treatment of both peripheral neuropathy and NHL may improve prognosis of patients.