The most common genes associated with ARVC are PKP2 (OMIM 602861), DSP (OMIM 125647), DSG2 (OMIM 125671), DSC2 (OMIM 125645), JUP (OMIM 173325), and TMEM43 (OMIM 612048). This evidence concerns the gene DSC2 and arrhythmogenic right ventricular cardiomyopathy.