DSG2 and arrhythmogenic right ventricular cardiomyopathy: The most common genes associated with ARVC are PKP2 (OMIM 602861), DSP (OMIM 125647), DSG2 (OMIM 125671), DSC2 (OMIM 125645), JUP (OMIM 173325), and TMEM43 (OMIM 612048).