Age, male, oral antidiabetic agents, insulin use, current smoking, current drinking, obesity, levels of triglycerides (TG), alanine aminotransferase (ALT), carbamide, eGFR, unconjugated bilirubin (IBiL), and β-blockers were significantly different across the GGT tertiles (all P < 0.05). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.