Recent studies in the secondary abiotic IL-10−/− mouse model infected with a C. jejuni htrA deletion mutant (11168ΔhtrA) showed notably less severe clinical symptoms and reduced intestinal as well as extra-intestinal immunopathological sequelae of infection as compared to 11168WT strain infected control mice (Heimesaat et al., 2014a). This evidence concerns the gene IL10 and infection.