NR4A1 and neoplasm: After additional adjusting for potential confounding tumor characteristics such as tumor size and hormone receptor (HR) status, a relationship between the rs11212617 genotype and the ability of treatment arms to achieve a pCR in patients remained significant (adjusted ORgenotype×arm = 20.53, 95%CI: 1.97–213.79, p = 0.011; Table S3).