IL4 and asthma: Some investigations in mice have shown that Hyssopus officinalis plays an anti-inflammatory role through regulating the secretion of IL-4, IL-6, IL-17, and IFN-gamma and correcting the imbalance in Th1/Th2, therefore, relieving cough and asthma (Javadi et al., 2017 ▶; Ma et al., 2014 ▶).