Chang et al. (2006) ▶ investigated the Chinese herbal medicine formula, STA-1 (consisting of 10 herbs as follows: root of Rehmannia glutinosa, root bark of Paeonia suffruticosa, fruit of Cornus officinalis, rhizome of Alisma orientalis, root of Dioscorea opposita, root of Ophiopogon japonicus, root of Glycyrrhiza uralensis, root of Panax quinquefolius and tuber of Pinellia ternate) for treatment of allergic asthma and showed a statistically significant reduction in symptoms' scores, systemic steroid usage, total IgE and specific IgE in the STA-1 group. Here, IGHE is linked to allergic asthma.