As a well‐known tumor suppressor, miR‐101 has multiple targets, including Fos, EZH2, Cox‐2, N‐myc, and Mcl‐1, that play roles in cancers 29, 30, 32, 33, 34, 35, indicating that the activity of miR‐101 is performed through various mechanisms by targeting different genes. The gene discussed is EZH2; the disease is cancer.