After C/EBPα antibody immunoprecipitation, the amount of DNA fragments amplified by different primer pairs (S1, primers for site 1; S3, primers for site 3; and S4, primers for site 4) significantly decreased in the LADC tissues compared with the adjacent non‐tumor tissues (Fig. 5D), indicating that the binding of C/EBPα with the GRK6 gene promoter in the LADC tissues was specific and inhibited. Here, GRK6 is linked to neoplasm.