For example, our ceRNA network showed that PIK3CG, SEMA6A, and IGF1 are the top three genes that interact with lncRNA RP11-284N8.3 Furthermore, siRNA silencing of RP11-284N8.3 in cancer cells led to decreases in PIK3CG, SEMA6A, and IGF1 mRNA (Figure 3(b)). This evidence concerns the gene IGF1 and cancer.