AKT1 and neoplasm: Previous studies revealed that FALEC contributed to carcinogenesis by trans-regulating the expression of genes such as P21 and AKT1 involved in the malignant proliferation, invasion, and metastasis of tumor cells (Hu X. et al., 2014; Zhong et al., 2015; Jeong et al., 2016; Ni et al., 2017; Pan et al., 2017; Zhao et al., 2017; Li B. et al., 2018; Li Y. et al., 2018; Wang et al., 2018).