Determination of influenza specific mucosal IgA revealed that mice from the PBS control group as well as mice immunized i.m. with non-adjuvanted or CAF01-adjuvanted WIV developed no or very low mucosal IgA responses (in nose and lungs) against any of the viruses (Figures 2A,B and Figures S3A,B,C). The gene discussed is CD79A; the disease is influenza.