By contrast, increased serum IgA levels or IgA autoantibodies have been reported in multiple (inflammatory) diseases including IgA nephropathy (IgAN), IgA vasculitis, dermatitis herpetiformis, celiac disease, inflammatory bowel disease (IBD), Sjögren's syndrome, ankylosing spondylitis, alcoholic liver cirrhosis, and Acquired immunodeficiency syndrome (7–9), although the role of IgA in pathology is still ill-understood. The gene discussed is CD79A; the disease is inflammatory bowel disease.