LRRK2 and Parkinson disease: Analysis of five large-scale GWAS datasets from Europe and the USA has identified some risk SNPs (p < 5.00E-08) through meta-analysis of PD susceptibility genes, including MAPT, SNCA, HLA-DRB5, BST1, GAK, LRRK2, SYT11, ACMSD, STK39, MCCC1/LAMP3, and CCDC62/HIP1R (13).