Autoantibodies for the GluA3 subunit of AMPARs have been identified both in the serum and CSF of FTD patients (Borroni et al., 2017), characterized by a bvFTD phenotype with presenile onset, absence of an autosomal dominant pattern of inheritance, and greater bitemporal atrophy. The gene discussed is GRIA3; the disease is frontotemporal dementia.