ULK1 and hepatocellular carcinoma: In hepatocellular carcinoma, overexpression of mir-26a/b inhibits autophagy induced by doxorubicin treatment through regulate ULK1 expression and also induces apoptosis to enhance cell chemosensitivity; On the other hand, low level of mir-26a confers chemoresistance via autophagy induction when cells were treated with doxorubicin [46].