We found that plasma MIF levels in patients with diabetes mellitus and nondiabetes STEMI could reflect the extent of impaired cardiac function in the acute phase, probably because MIF levels in the early stage of infarction could reflect the myocardial infarct size indicated by myocardial zymogram changes and imaging [3, 7] and the size of myocardial infarction is one of the main factors that affected acute cardiac function impairment after myocardial infarction. The gene discussed is MIF; the disease is myocardial infarction.