A higher mutation burden in BRCA1 was also reported in other studies in patients with a cancer history or unselected patients in Asian population.16, 17 Besides, 8.5% of patients carried non‐BRCA1/2 pathogenic mutations, which were mainly found in ATM, CHEK2, PALB2, and BRIP1 genes.7 Previous studies have reported that approximately 11.4% of BC patients carried mutations in non‐BRCA1/2 genes.8 It is worthnoting that rare mutations of BRIP1 c.2392C > T was detected in one patient in our cohort. The gene discussed is CHEK2; the disease is breast cancer.