We also found knockdown of MNX1‐AS1 promoted E‐cadherin mRNA expression whereas it inhibited N‐cadherin and vimentin mRNA expression in DU145 and PC3 cells compared with the control, indicating that MNX1‐AS1 might induce the migration and invasion of prostate cancer cells via regulating EMT (Fig. 4A). This evidence concerns the gene MNX1 and prostate cancer.