Firstly, the number of prostatic cells passed through the transwell membrane was observed to be reduced by siRNA‐mediated knockdown of MNX1‐AS1, suggesting that down‐regulation of MNX1‐AS1 could inhibit prostatic cancer cell migration in vitro (P < 0.01; Fig. 3A). This evidence concerns the gene MNX1 and Familial prostate cancer.