Moreover, high expression of SIX3 was associated with improved overall and progression‐free survival of patients with lung adenocarcinoma.32 A similar finding was also observed in patients with glioblastoma.33 A meta‐analysis suggests that SIX3 may play a role in suppressing the progression of lung cancer, especially in its early stage.34 Here, SIX3 is linked to lung adenocarcinoma.