In alveolar rhabdomyosarcoma, for example, high expression of cytoplasmic and nuclear YAP1 has been documented, and the fusion oncogene paired box gene 3 (PAX3): forkhead box protein O1 (FOXO1) directly regulates increased expression of Ras‐association domain family 4 (RASS4). The gene discussed is FOXO1; the disease is rhabdomyosarcoma.