Moderate or strong nuclear YAP1 expression was confirmed in 77 (91%) of 85 primary MLS samples, and YAP1 co‐localized with FUS:DDIT3 in the nucleus of MLS cells, indicating that YAP1 and FUS:DDIT3 closely cooperate to orchestrate a gene expression program that promotes MLS development (Fig. 1). This evidence concerns the gene DDIT3 and McLeod neuroacanthocytosis syndrome.