Furthermore, in a lymphoma xenograft model, HP-MR using pyruvate evaluated the LDH-A and glutaminase (GLS) inhibition by small molecule drugs FX11 and BPTES [bis-2-(5-phenylacetamido-1,2,4-diathiazol-2-yl) ethyl sulfide] respectively [8]. This evidence concerns the gene GLS and lymphoma.