SMOX and infection: Extensive accumulation of TAMRA-LL-37 throughout the cytoplasm (white arrows; Fig 5D) only occurred in cells associated with PAO1 aggregates, and those cells were found to have ~4-fold greater level of associated PAO1 aggregates than cells in which LL-37 had not accumulated (S4 Fig), demonstrating an association between magnitude of infection and high level accumulation of intracellular LL-37.