Five fatty liver disease-associated SNPs (rs780094 (GCKR), rs2281135 (PNPLA3), rs8418 (PNPLA3), rs58542926 (TM6SF2), rs2980875 (TRIB1)) passed the significance threshold of <0.05 (Table 5) and were directionally consistent with previous studies. The gene discussed is PNPLA3; the disease is fatty liver disease.