ALMS1 is mutated in the autosomal recessive disease Alstrom Syndrome, and required for the normal function of primary cilia in multiple tissues, including the liver.28 The patient was heterozygous for the ALMS1 mutation L525_T527delinsP, which replaces L525‐E526‐T527 with a helix destabilizing proline. The gene discussed is ALMS1; the disease is Alstrom syndrome.