In addition, ACSM2A has not been associated with hyperammonemia and has an allele frequency of 0.18 in East Asians (https://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?searchType=adhoc_search&type=rs&rs=rs59261767). This evidence concerns the gene ACSM2A and Hyperammonemia.