The study of Richter et al confirmed that tumor succinate:fumarate ratios were higher in tumors of patients with SDHB mutations compared to tumors of patients with an SDHC/D mutation.87 EMT is a process by which epithelial cells lose their polarity and cell‐to‐cell adhesion, thereby gaining migratory and invasive properties to become mesenchymal stem cells. This evidence concerns the gene SDHB and neoplasm.