WWTR1 and neoplasm: As shown in Fig. 1a, the average IHC staining score of WWTR1 in the GCA tumor tissue is 94.67 ± 74.82 while in the normal tissue is 70.84 ± 57.04 (p = 0.0002), indicating that expression of WWTR1 is significantly higher in the tumor tissue than in the normal tissue.