TP53 and fibrosarcoma: For example, HT1080 fibrosarcoma, Rh30 and Rh41 rhabdomyosarcoma, as well as immortalized p53-null fibroblasts MDAH041 were sensitive, whereas epithelial cells (MCF7, HCT116, retinal pigmented epithelium:RPE) were not easily killed by these compounds (Fig. 5E and ref.11).