MCL has been shown to inhibit glioma cell growth by inducing apoptosis in colitis-associated cancer cells [2], activate pyruvate kinase M2 (PKM2) to suppresses leukaemia [1], suppress LPS-induced neuroinflammatory responses [3], and alleviate liver steatosis in diabetic mice by reducing inflammation and amplifying autophagy [8]. The gene discussed is PKM; the disease is central nervous system cancer.