Intriguingly, correlative analysis of GPS2 and PPARA expression with the 72 GPS2-sensitive and NASH-related genes in the dataset from 104 human NASH patients showed an overall opposite correlation (Fig. 6g), while GPS2 and PPARA expression was not correlated (Supplementary Fig. 6j). This evidence concerns the gene GPS2 and metabolic dysfunction-associated steatohepatitis.